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Home▶Archive▶Vol. 42 No. 3 (2025)▶Patterns of Histopathological Changes in Kidney in…
Print ISSN 0971-1929 · Online ISSN 0974-4568
Case Report

Patterns of Histopathological Changes in Kidney in Phosphorus  Poisoning- An Autopsy Finding

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Sapna Patel — Associate Professor, Department of Pathology, JSS medical college, Mysore
Pallavi BR — Senior Resident, Department of Pathology, JSS medical college, Mysore
Smitha Rani
Kushala P
Published 16 Oct 2025 Vol. 42 No. 3 (2025), pp. 135-137
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Abstract

Background Yellow phosphorus is a toxic, nonmetallic inorganic substance used in various sectors, such as fireworks, firecrackers,  rodenticides, ammunition, match industries and fertilizers. We report a case of phosphorus poisoning with  histopathological changes in the kidney. Case description An 18 years old male died from the consumption of rat poison (contains yellow phosphorous). On postmortem  examination, yellowish discoloration was seen all over the body. Internal examination showed edematous brain.  Yellowish discoloration with hemorrhagic areas was seen in the cerebellum along with yellowish discoloration of both  liver and kidney. On histopathological examination of kidney, the proximal tubular epithelial cells were predominantly  affected by diffuse cytoplasmic vacuolation. Glomerular epithelial cells showed cloudy swelling. No significant interstitial  inflammation/tubulitis was seen. 

 

KeywordsYellow phosphorouspoisoninghistopathologyproximal tubular epithelial cellsglomeruli

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