Incidental Finding of Neurofibromatosis Type 1 in a Case of Poisoning: A Medico-legal Case Report
DOI:
https://doi.org/10.48165/jfmt.2026.43.03.23Keywords:
Neurofibromatosis type 1, Plexiform neurofibroma, Café-au-lait spots, Medico-legal autopsy, Unknown poisoningAbstract
Neurofibromatosis type 1 (NF1), also known as von Recklinghausen’s disease, is an autosomal dominant disorder with a prevalence of approximately 1 in 3000 to 4000 individuals worldwide. We report a case of neurofibromatosis type 1 (NF1) identified during medico-legal autopsy of a deceased married female with antecedent history of unknown poisoning, later confirmed as Celphos ingestion. External examination revealed multiple café-au-lait macules (>6), cutaneous neurofibromas on the trunk, and a large diffuse swelling over the left thigh consistent with plexiform neurofibroma. Gross and histopathological findings confirmed the diagnosis. Familial occurrence was noted, as similar features were present in her daughter. This case emphasizes the importance of recognizing NF1 in forensic practice and documenting hereditary disorders during autopsy.
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